Idebenone acts against growth of Helicobacter pylori by inhibiting its respiration.
نویسندگان
چکیده
Growth of Helicobacter pylori was inhibited by the quinones, idebenone, duroquinone, menadione, juglone, and coenzyme Q(1) at low concentrations of 0.8 to 3.2 mug/ml. Idebenone specifically inhibited H. pylori growth by inhibiting respiration and decreasing the cellular ATP level. The respiratory inhibition was accompanied by reduction of idebenone by the H. pylori cells.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 50 6 شماره
صفحات -
تاریخ انتشار 2006